Order Oxycodone 30MG Without Delay.Oxycodone, sold under the brand name Roxicodone and OxyContin (which is the extended-release form) among others, is a semi-synthetic opioid used medically for the treatment of moderate to severe pain. It is highly addictive^[15] and is a commonly abused drug.^[16]^[17] It is usually taken by mouth, and is available in immediate-release and controlled-release formulations.^[16] Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation.^[16] In the United Kingdom, it is available by injection.^[18] Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.^[16]

Common side effects include euphoria, constipation, nausea, vomiting, loss of appetite, drowsiness, dizziness, itching, dry mouth, and sweating.^[16] Side effects may also include addiction and dependence, substance abuse, irritability, depression or mania, delirium, hallucinations, hypoventilation, gastroparesis, bradycardia, and hypotension.^[16] Those allergic to codeine may also be allergic to oxycodone.^[16] Use of oxycodone in early pregnancy appears relatively safe.^[16] Opioid withdrawal may occur if rapidly stopped.^[16] Oxycodone acts by activating the μ-opioid receptor.^[19] When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine.^[20]

Oxycodone was originally produced from the opium poppy opiate alkaloid thebaine in 1916 in Germany. One year later, it was used medically for the first time in Germany in 1917.^[21] It is on the World Health Organization’s List of Essential Medicines.^[22] It is available as a generic medication.^[16] In 2022, it was the 60th most commonly prescribed medication in the United States, with more than 11 million prescriptions.^[23]^[24] A number of abuse-deterrent formulations are available, such as in combination with naloxone or naltrexone.^[17]^[25]