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- Medical Uses: Prescribed for panic disorder, epilepsy, and seizure prevention (such as absence seizures or Lennox-Gastaut syndrome).
- Mechanism: Enhances the effects of GABA, a natural calming chemical in the brain and nerves.
- Dependence and Withdrawal: This drug can form habits. Stopping treatment suddenly can trigger severe withdrawal, including seizures, shaking, and severe anxiety.
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Description
Clonazepam is used alone or together with other medicines to treat certain seizure disorders (eg, Lennox-Gastaut syndrome, akinetic, myoclonic, and absence seizures). It is also used to treat panic disorder. Clonazepam is a benzodiazepine that works in the brain to prevent seizures. Benzodiazepines are central nervous system (CNS) depressants, which are medicines that slow down the nervous system.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
This medicine is available only with your doctor’s prescription.
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This product is available in the following dosage forms:
- Tablet, Disintegrating
- Tablet
Before Using
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clonazepam in children with seizure disorders. However, safety and efficacy in children with panic disorder have not been established.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of clonazepam in the elderly. However, elderly patients are more likely to have confusion and severe drowsiness, or age-related heart, liver, or kidney problems, which may require caution and an adjustment in the dose for patients receiving clonazepam.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
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Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
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- Flumazenil
- Isocarboxazid
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acepromazine
- Alfentanil
- Alprazolam
- Amobarbital
- Anileridine
- Aripiprazole
- Aripiprazole Lauroxil
- Asenapine
- Baclofen
- Benperidol
- Benzhydrocodone
- Bromazepam
- Bromopride
- Buprenorphine
- Buspirone
- Butabarbital
- Butalbital
- Butorphanol
- Calcifediol
- Calcium Oxybate
- Cannabidiol
- Cannabis
- Carbamazepine
- Carbidopa
- Carbinoxamine
- Carisoprodol
- Carphenazine
- Ceritinib
- Cetirizine
- Chloral Hydrate
- Chlordiazepoxide
- Chlorpromazine
- Chlorzoxazone
- Clobazam
- Clomipramine
- Clorazepate
- Clozapine
- Codeine
- Cyclobenzaprine
- Cyproheptadine
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Amiodarone
- Desipramine
- Ginkgo
- Rifapentine
- Ritonavir
- St John’s Wort
- Theophylline
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
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Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Alcohol or drug abuse or dependence, or history of or
- Depression, history of or
- Lung or breathing problems or
- Porphyria—Use with caution. May make these conditions worse.
- Glaucoma, narrow angle, acute or
- Liver disease—Should not be used in patients with these conditions.
- Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Proper Use
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence).
This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Swallow the tablet whole with water.
If you are using the disintegrating tablet (wafer), make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may take a sip of water.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage forms (tablets or disintegrating tablets):
- For seizures:
- Adults and children 10 years and older—At first, 0.5 milligram (mg) 3 times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day.
- Children up to 10 years or 30 kilograms (kg) of body weight—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.01 to 0.03 mg per kg of body weight per day, given in 2 or 3 divided doses. However, the dose is usually not more than 0.05 mg per kg of body weight. Your doctor may adjust your dose as needed.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
- For panic disorder:
- Adults—At first, 0.25 milligram (mg) 2 times per day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 4 mg per day.
- Children—Use and dose must be determined by your doctor.
- For seizures:
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Missed Dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Precautions
It is very important that your doctor check your progress at regular visits to see if the medicine is working properly and to allow for changes in the dose. Blood tests may be needed to check for unwanted effects.
Tell your doctor if you are pregnant or planning to become pregnant. Using this medicine during the later pregnancy may cause problems in your newborn baby (eg, sedation or withdrawal symptoms). Tell your doctor right away if your baby has an abnormal sleep pattern, diarrhea, feeding problems, a high-pitched cry, irritability, low muscle tone, restlessness, shakiness or tremors, sluggishness, trouble breathing, weight loss, vomiting, or fails to gain weight. If you think you have become pregnant while using the medicine, tell your doctor right away.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
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This medicine may cause drowsiness, trouble with thinking, trouble with controlling movements, or trouble with seeing clearly. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to think or see well.
If you develop any unusual and strange thoughts or behavior while you are taking clonazepam, be sure to discuss it with your doctor. Some changes that have occurred in people taking this medicine are like those seen in people who drink alcohol and then act in a manner that is not normal. Other changes may be more unusual and extreme, such as confusion, worsening of depression, hallucinations (seeing, hearing, or feeling things that are not there), suicidal thoughts, and unusual excitement, nervousness, or irritability.
If you have been taking this medicine for a long time, do not stop taking it without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, including actions that are out of control, anxiety, blurred vision, decreased awareness or responsiveness, discouragement, dizziness, environment seems unreal, feeling of unreality, feeling sad or empty, irritability, lack of appetite, loss of interest or pleasure, mimicry of speech or movements, mutism, negativism, nervousness, peculiar postures or movements, mannerisms or grimacing, seeing, hearing, or feeling things that are not there, sense of detachment from self or body, seizures, severe sleepiness, talking, feeling, and acting with excitement, trouble concentrating and sleeping.
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Symptoms of an overdose include: change in consciousness, changes in patterns and rhythms of speech, hallucinations, lack of coordination, loss of consciousness, loss of strength or energy, mood or mental changes, muscle pain or weakness, nightmares, sleepiness or unusual drowsiness, shakiness and unsteady walk, slurred speech, trouble in speaking, trouble sleeping, unsteadiness, trembling, or other problems with muscle control or coordination, unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness, unusual excitement, nervousness, restlessness, or irritability, or unusual weak feeling. Call your doctor right away if you notice these symptoms.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
This medicine will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system, which may cause drowsiness or make you less alert. Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, barbiturates or seizure medicines, muscle relaxants, or anesthetics (numbing medicines), including some dental anesthetics. Check with your doctor before taking any of these products while you are using this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Clonazepam (Klonopin) – Uses, Side Effects, and More
- Common Brand Name(s): Klonopin
- Common Generic Name(s): clonazepam
- Pronunciation: kloe-NAZ-e-pam, KLON-oh-pin
- Drug Classes: anticonvulsant, anxiolytic, benzodiazepine
- Availability: prescription only, controlled substance, generic available
- How is it used? tablet that is swallowed, tablet that dissolves in the mouth
Uses
What is clonazepam used for?
Clonazepam is commonly used to treat the following conditions.
- Certain types of seizure disorders, also called epilepsy
- Panic disorder with or without the fear of open spaces, also called agoraphobia
Clonazepam may also be used for other conditions as determined by your health care provider.
How does clonazepam work (mechanism of action)?
Clonazepam produces a calming effect on the brain and nerves, which helps to reduce anxiety, prevent seizures, and promote relaxation.
How is clonazepam supplied (dosage forms)?
Brands and other names
- Klonopin
- Klonopin Wafers
Dosage forms and strengths
- 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, 2 mg orally disintegrating tablets
- 0.5 mg, 1 mg, 2 mg oral tablets
How should I store clonazepam?
Clonazepam should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place, in a tightly closed container.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
Side Effects
What are the most common side effects of clonazepam?
The most common side effects of clonazepam are listed below. Tell your health care provider if you have any of these side effects that bother you.
- Drowsiness
- Problems with walking and coordination
- Dizziness
- Depression
- Tiredness (fatigue)
- Problems with memory or concentration
There may be other side effects of clonazepam that are not listed here. Contact your health care provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088 (800-332-1088). In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
What are the serious side effects of clonazepam?
While less common, the most serious side effects of clonazepam are described below, along with what to do if they happen.
Severe Allergic Reactions. Clonazepam can cause allergic reactions, which can be serious. Stop taking clonazepam and get help right away if you have any of the following symptoms of a serious allergic reaction.
- Breathing problems or wheezing
- Racing heart
- Fever or general ill feeling
- Swollen lymph nodes
- Swelling of the face, lips, mouth, tongue, or throat
- Trouble swallowing or throat tightness
- Itching or skin rash
- Bumps on the skin called hives that can be red, pink, white, or brown depending on your skin tone
- Nausea or vomiting
- Dizziness, feeling lightheaded, or fainting
- Stomach cramps
- Joint pain
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Suicidal Thoughts and Actions. Clonazepam may cause suicidal thoughts or actions in a small number of people. If you’re about to harm yourself, call 911 or call or text 988, the Suicide & Crisis Lifeline. Call your health care provider right away if you have any of the following symptoms.
- New or increased thoughts of suicide or death
- Suicide attempt
- New or increased feelings of anxiety, depression, or other unusual changes in mood or behavior
Risk of Misuse and Addiction. Misuse of clonazepam can lead to serious side effects including coma or death. Misuse means taking a medicine in a way other than how it was prescribed. Take clonazepam exactly as prescribed. Tell your health care provider if you feel that clonazepam is not working. Call your health care provider right away or go to the nearest emergency room if you experience any of the following serious symptoms.
- Sudden confusion or feeling disoriented
- Feeling paranoid
- Suicidal thoughts or actions
- Seizures
- Trouble breathing
Dependence and Withdrawal Reactions. Clonazepam can cause physical dependence, which means your body relies on the medicine to function properly. If you stop clonazepam suddenly, it could lead to withdrawal symptoms, which may be life-threatening. Do not stop taking clonazepam without talking with your health care provider. Your health care provider will tell you how to stop clonazepam to reduce the risk of withdrawal reactions. Call your health care provider right away or go to the nearest emergency room if you experience any of the following serious symptoms.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
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- Unusual movements, responses, or expressions
- Seizures
- Sudden and severe mental or nervous system changes
- Seeing or hearing things that others do not see or hear, also called hallucinations
- An extreme increase in activity or talking
- Losing touch with reality
Some people may experience the following symptoms of a withdrawal reaction that can last for several weeks to more than 12 months.
- Anxiety
- Trouble remembering, learning, or concentrating
- Depression
- Problems sleeping
- Feeling like insects are crawling under the skin
- Weakness
- Shaking
- Muscle twitching
- Burning or prickling feeling in the hands, arms, legs, or feet
- Ringing in the ears
Risk With Opioid Medicines. Taking clonazepam with an opioid medicine, such as codeine, morphine, and oxycodone, may lead to severe drowsiness, breathing problems, coma, and death. Get emergency help right away if you experience the following symptoms.
- Slow or shallow breathing
- Breathing stops (which may lead to the heart stopping)
- Excessive sleepiness or trouble staying awake
Decreased Alertness or Coordination. Clonazepam can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how clonazepam affects you.
WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS
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- Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. Reserve concomitant prescribing of these drugs for patients for whom alternative treatment options are inadequate. Limit dosages and durations to the minimum required. Follow patients for signs and symptoms of respiratory depression and sedation (see WARNINGS and PRECAUTIONS).
- The use of benzodiazepines, including Klonopin, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. Abuse and misuse of benzodiazepines commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes. Before prescribing Klonopin and throughout treatment, assess each patient’s risk for abuse, misuse, and addiction (see WARNINGS).
- The continued use of benzodiazepines, including Klonopin, may lead to clinically significant physical dependence. The risks of dependence and withdrawal increase with longer treatment duration and higher daily dose. Abrupt discontinuation or rapid dosage reduction of Klonopin after continued use may precipitate acute withdrawal reactions, which can be life-threatening. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue Klonopin or reduce the dosage (see DOSAGE AND ADMINISTRATION and WARNINGS).Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
Klonopin is a brand-name drug prescribed to treat panic disorder (with or without agoraphobia) in adults and certain seizure disorders in adults and children of all ages.
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The active ingredient in Klonopin is clonazepam. Klonopin belongs to a drug class called benzodiazepines.
This article describes the dosages of Klonopin, as well as its strengths and how to take the medication.
Your doctor will likely prescribe a low dosage to start. Then they’ll adjust it over time to reach the amount that’s right for you. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. This is as a maintenance (regular) dosage.
The following dosage chart summarizes typical Klonopin’s dosages in adults. All doses are listed in milligrams (mg).
Always be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs. In some cases, doctors may adjust your dosage from those shown here.
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| Condition | Starting dosage | Maintenance dosage |
|---|---|---|
| panic disorder | 0.25 mg twice per day | 0.5 mg twice per day |
| seizure disorder | 0.5 mg three times per day | specific to the individual |
Keep reading for more dosage details.
Klonopin form
Clonazepam is available as an oral tablet.
Klonopin strengths
Klonopin comes in three strengths:
- 0.5 mg
- 1 mg
- 2 mg
The recommended starting dosage of Klonopin for panic disorder in adults is 0.25 mg twice per day. This is likely the lowest dose of Klonopin your doctor will prescribe. Starting with the smallest dose helps your body adjust to the medication. It also helps your doctor see how well the drug is working for you.
Your doctor may monitor you for the first 3 days after you start treatment with Klonopin to see if the smallest dose is working for you. In some cases, they may recommend a dose increase every 3 days until the drug is working to manage your symptoms.Buy Klonopin (Clonazepam) Online to Treat epilepsy USA
The typical maintenance dosage for panic disorder is 0.5 mg twice per day. However, for some people, doctors prescribe the maximum daily dose of 4 mg of Klonopin (2 mg twice per day) to effectively manage the condition. This is the highest dosage of Klonopin in recommendation for panic disorder.
Always follow your prescribing doctor’s instructions. Notify them if you experience any side effects that may prevent you from taking your medication.
